Raquel Medialdea Carrera

Improving the diagnosis of emergent zoonotic infections such as Zika Virus

Personal Statement:

Raquel graduated in Biotechnology at the University of Oviedo (Spain) and holds an MSc in Translational Medicine from the University of Glasgow and an Mres in Infections and Global Health from the University of Liverpool.

 

Her interest in emergent and zoonotic infections took her to help with the Ebola Outbreak in Sierra Leone in 2015 and to work in Brazil during the Zika and Chikungunya outbreaks. Raquel is also believes that is fundamental to share research findings through public engagement and science communication to all audiences.

          

 

Raquel Medialdea Carrera

Lay Summary:

Over the last decades, several emerging infectious diseases have caused epidemics worldwide such as Ebola, Zika, Chikungunya, Dengue. Accurate diagnosis of this dangerous viruses is fundamental to improve management of patients affected as well as to design vaccine strategies and improve prevention.

Having worked in Sierra Leone, Brazil and India over the last 3 years, we have tried to optimise, evaluate and improve the existing methods to detect this viruses in the population. My research has also focussed trying to understand the link between viruses such as Zika or Chikungunya and neurologic diseases such as encephalitis or Guillain-Barre Syndrome. In addition, we have worked in  understanding the seroprevalence of emergent pathogens such as Zika, Dengue and Chikungunya in Brazil. This will help understanding the risk for this population to future outbreaks.


Supervisors:

  • Mike Griffiths - Institute of Infection and Global Health, University of Liverpool
  • Tom Solomon – NIHR Health Protection Research Unit in Emerging and Zoonotic Infections, University of Liverpool
  • Nick Beeching – NIHR Health Protection Research Unit in Emerging and Zoonotic Infections, Liverpool School of Tropical Medicine
  • Tim Brooks – NIHR Health Protection Research Unit in Emerging and Zoonotic Infections, Public Health England

Publications:

Mehta R, Soares CN, Medialdea-Carrera R, Ellul M, da Silva MTT, Rosala-Hallas A, et al. (2018) The spectrum of neurological disease associated with Zika and chikungunya viruses in adults in Rio de Janeiro, Brazil: A case series. PLoS Neglected Tropical Diseases 12(2): e0006212.
https://doi.org/10.1371/journal.pntd.0006212

Balsameda, A; Stettler, K, Medialdea-Carrera, Raquel et al., (2017) Antibody-based assay discriminates Zika virus infection from other flaviviruses. PNAS, 114, 31

Soares, C. Brasil, P., Medialdea-Carrera, Raquel, Sequeria, P. et al. (2016) Fatal encephalitis associated with Zika virus infection in an adult. Journal of Clinical Virology 83: 63-65
https://www.sciencedirect.com/science/article/pii/S1386653216305133