Publications: 2021
21 Dec 2021
Community transmission and viral load kinetics of the SARS-CoV-2 delta (B.1.617.2) variant in vaccinated and unvaccinated individuals in the UK: a prospective, longitudinal, cohort study
HPRU Author:
Jake Dunning
06 Dec 2021
Communicating uncertainty in epidemic models
HPRU-EZI Authors -
Ruth McCabe;
Christl Donnelly
03 Dec 2021
Estimating vaccination threshold and impact in the 2017-2019 hepatitis A virus outbreak among persons experiencing homelessness or who use drugs in Louisville, Kentucky, United States
HPRU-EZI Authors -
Christl Donnelly
23 Nov 2021
Ten months of temporal variation in the clinical journey of hospitalised patients with COVID-19: An observational cohort
HPRU-EZI Authors -
Jake Dunning;
Christl Donnelly;
Peter Horby;
Mark Pritchard
22 Nov 2021
Prospective validation of the 4C prognostic models for adults hospitalised with COVID-19 using the ISARIC WHO Clinical Characterisation Protocol
HPRU Authors:
Calum Semple; Jake Dunning; Tom Solomon; Peter Horby; Lance Turtle
18 Nov 2021
The impact of viral mutations on recognition by SARS-CoV-2 specific T cells
HPRU-EZI Authors:
Calum Semple,
Lance Turtle
18 Oct 2021
Acute kidney injury in patients hospitalized with COVID-19 from the ISARIC WHO CCP-UK Study: a prospective, multicentre cohort study
HPRU-EZI Authors -
Calum Semple,
Jake Dunning
14 Oct 2021
The impact of viral mutations on recognition by SARS-CoV-2 specific T cells
HPRU-EZI Author -
Lance Turtle
12 Oct 2021
Transmission dynamics of SARS-CoV-2 in the hospital setting
HPRU Author:
Christl Donnelly
07 Oct 2021
COVID-19–Associated Orphanhood and Caregiver Death in the United States
HPRU-EZI Authors -
Christl Donnelly
08 Sep 2021
Long Covid in adults discharged from UK hospitals after Covid-19: A prospective, multicentre cohort study using the ISARIC WHO Clinical Characterisation Protocol
HPRU-EZI Authors -
Calum Semple,
Lance Turtle
25 Aug 2021
Differential impact of the COVID-19 pandemic on laboratory reporting of norovirus and Campylobacter in England: A modelling approach. PLoS One [Internet]. 2021;16(8)
HPRU-EZI Authors -
Roberto Vivancos
17 Aug 2021
Two doses of SARS-CoV-2 vaccination induce robust immune responses to emerging SARS-CoV-2 variants of concern.
HPRU-EZI Authors -
Miles Carroll
16 Aug 2021
A comparison of persistence of SARS-CoV-2 variants on stainless steel
HPRU Author:
Jake Dunning
16 Aug 2021
Clinical review of cerebral venous thrombosis in the context of COVID-19 vaccinations: Evaluation, management, and scientific questions
HPRU Author:
Tom Solomon
09 Aug 2021
Investigation of SARS-CoV-2 Faecal Shedding in the Community: A Prospective Household Cohort Study (COVID-LIV) in the UK - BMC Infectious Diseases (2021) 21:784
HPRU-EZI Authors -
Adams Emily R.
Turtle Lance.
Solomon Tom.
French Neil.
06 Aug 2021
Considerations for causality assessment of neurological and neuropsychiatric complications of SARS-CoV-2 vaccines: from cerebral venous sinus thrombosis to functional neurological disorder. J Neurol Neurosurg Psychiatry. 2021;jnnp-2021-326924.
HPRU-EZI Authors -
Tom Solomon.
06 Aug 2021
Cerebral venous thrombosis after vaccination against COVID-19 in the UK: a multicentre cohort study. Lancet. 2021;6736(21):1–10
HPRU-EZI Authors -
Tom Solomon
04 Aug 2021
Subacute Cognitive Impairment in Individuals With Mild and Moderate COVID-19: A Case Series. Frontiers in Neurology. 2021;12
HPRU-EZI Authors - Solomon, Tom
02 Aug 2021
Co-Infections, Secondary Infections, and Antimicrobial Usage in Hospitalised Patients with COVID-19 from the ISARIC WHO CCP-UK Study: A Prospective, Multicentre Cohort Study
HPRU Authors:
Calum Semple,
Jake Dunning,
Lance Turtle
29 Jul 2021
Obesity, Ethnicity, and Risk of Critical Care, Mechanical Ventilation, and Mortality in Patients Admitted to Hospital with COVID-19: Analysis of the ISARIC CCP-UK Cohort
HPRU Author:
Calum Semple
21 Jul 2021
Protocol for DexEnceph: a randomised controlled trial of dexamethasone therapy in adults with herpes simplex virus encephalitis BMJ Open 2021:11
HPRU-EZI Authors -
TomSolomon.
19 Jul 2021
Metagenomic identification of a new sarbecovirus from horseshoe bats in Europe. Sci Rep [Internet]. 2021;11(1):1–9.
HPRU-EZI Authors -
Crook, Jack M.
Carroll, Miles
Vipond, Richard
17 Jul 2021
Characterisation of in-hospital complications associated with COVID-19 using the ISARIC WHO Clinical Characterisation Protocol UK: a prospective, multicentre cohort study
HPRU Author:
Calum Semple,
Lance Turtle,
Jake Dunning
16 Jul 2021
One hundred years of zoonoses research in the Horn of Africa: A scoping review. PLoS Negl Trop Dis. 2021;15(7)
HPRU-EZI Authors -
Maya Wardeh,
Matthew Baylis,
15 Jul 2021
Neurological manifestations of SARS-CoV-2 infection in hospitalised children and adolescents in the UK: a prospective national cohort study. Lancet Child Adolesc Heal [Internet]. 2021;4642(21):1–11.
HPRU-EZI Authors -
Tom Solomon.
08 Jul 2021
Prevalence of neutralising antibodies against SARS-CoV-2 in acute infection and convalescence: A systematic review and meta-analysis. PLoS Negl Trop Dis. 2021;15(7):
HPRU-EZI Authors -
Adams, Emily R.,
Cuevas, Luis E.
28 Jun 2021
Understanding norovirus reporting patterns in England : a mixed model approach
HPRU Author:
Roberto Vivancos
25 Jun 2021
Divide-and-conquer: machine-learning integrates mammalian and viral traits with network features to predict virus-mammal associations
HPRU Author:
Matthew Baylis
25 Jun 2021
COVID-19 symptoms at hospital admission vary with age and sex: results from the ISARIC prospective multinational observational study
HPRU Author:
Calum Semple
15 Jun 2021
Divergent trajectories of antiviral memory after SARS-Cov-2 infection
HPRU-EZI Authors -
Lance Turtle.
15 Jun 2021
The future of Japanese encephalitis vaccination: expert recommendations for achieving and maintaining optimal JE control
HPRU Author:
Tom Solomon
05 Jun 2021
Clinical review of cerebral venous thrombosis in the context of COVID-19 vaccinations: Evaluation, management, and scientific questions
Thakur, Kiran T.
Tamborska, Arina
Wood, Greta K.
McNeill, Emily
Roh, David
Akpan, Imo J.
Miller, Eliza C.
Bautista, Alyssa
Claassen, Jan
Kim, Carla Y.
Guekht, Alla
Pardo, Carlos A.
Williams, Olajide
García-Azorín, David
Prasad, Kameshwar
Schmutzhard, Erich
Michael, Benedict D.
Chou, Sherry H.-Y.
Winkler, Andrea S.
Solomon, Tom
Elkind, Mitchell S.
03 Jun 2021
Co-Infections, Secondary Infections, and Antimicrobial Usage in Hospitalised Patients with COVID-19 from the ISARIC WHO CCP-UK Study: A Prospective, Multicentre Cohort- Lancet Microbe
HPRU-EZI Authors -
Turtle, Lance
Dunning, Jake
Semple, Malcolm
03 Jun 2021
Neurology and neuropsychiatry of COVID-19: a systematic review and meta-analysis of the early literature reveals frequent CNS manifestations and key emerging narratives
HPRU Author:
Tom Solomon
27 May 2021
Convalescent plasma in patients admitted to hospital with COVID-19 (RECOVERY): a randomised controlled, open-label, platform trial
HPRU-EZI Authors:
Peter Horby
21 May 2021
Blood-feeding ecology of mosquitoes in two zoological gardens in the United Kingdom
HPRU Author:
Matthew Baylis
19 May 2021
Identifying how COVID-19-related misinformation reacts to the announcement of the UK national lockdown: An interrupted time-series study
HPRU-EZI Authors -
Sally Sheard;
John Tulloch;
Roberto Vivancos
18 May 2021
The microbiome and mosquito vectorial capacity: rich potential for discovery and translation
Cintia Cansado-Utrilla , Serena Y. Zhao , Philip J. McCall , Kerri L. Coon and Grant L. Hughes
18 May 2021
Evaluating clinical characteristics studies produced early in the Covid-19 pandemic: A systematic review. PLoS One 2021;16(5)
HPRU-EZI Authors -
Tom Solomon;
Peter W Horby;
Mark Pritchard
14 May 2021
Changes in in-hospital mortality in the first wave of COVID-19: a multicentre prospective observational cohort study using the WHO Clinical Characterisation Protocol UK
HPRU-EZI Authors:
Jake Dunning; Lance Turtle; Peter Openshaw; Malcolm G Semple
04 May 2021
Tocilizumab in patients admitted to hospital with COVID-19 (RECOVERY): a randomised, controlled, open-label, platform trial
HPRU-EZI Author:
Peter Horby
26 Apr 2021
Inactivation of SARS-CoV-2 on surfaces and in solution with Virusend (TX-10), a novel disinfectant
Enyia R. Anderson, Grant L. Hughes, Edward I. Patterson
23 Apr 2021
Pathologic Antibodies to Platelet Factor 4 after ChAdOx1 nCoV-19 Vaccination.
Singh, Deepak, Lown, Robert. Poles, Anthony. Solomon, Thomas. Levi, Marcel. Goldblatt, David.
Kotoucek, Pavel. Thomas, William. Lester, William.
23 Apr 2021
Perspectives on COVID-19 testing policies and practices: a qualitative study with scientific advisors and NHS health care workers in England
Anne-Marie Martindale
Caitlin Pilbeam
Hayley Mableson
Sarah Tonkin-Crine
Paul Atkinson
Aleksandra Borek
Suzie Lant
Nina Gobat
Tom Solomon
Sally Sheard
09 Apr 2021
Approaches to understanding COVID‐19 and its neurological associations
Beghi, Ettore
Michael, Benedict D.
Solomon, Tom
Westenberg, Erica
Winkler, Andrea S.
Beghi, Ettore
Michael, Benedict D.
Solomon, Tom
Westenberg, Erica
Winkler, Andrea S.
Knauss, Samuel
Sejvar, Jim
Siddiqi, Omar
Netravathi, M
Charway‐Felli, Augustina
Abd‐Allah, Foad
Bassetti, Claudio
Ferreira, Maria Lúcia Brito
Chou, Sherry Hsiang‐Yi
Dalmau, Josep
Delgado‐García, Guillermo
Easton, Ava
Emmrich, Julius
Endres, Matthias
Fleury, Agnès
Frontera, Jennifer A.
García‐Azorín, David
Guekht, Alla
Helbok, Raimund
Hellwig, Kerstin
Höglinger, Günter
Hoo, Fan Kee
Klein, Christine
Lant, Suzannah
McNett, Molly
Moro, Elena
Padovani, Alessandro
Pfausler, Bettina
Prasad, Kameshwar
Roman, Gustavo C.
Sarfo, Fred S.
Satishchandra, Parthasarathy
Saylor, Deanna
Spatola, Marianna
Spencer, Peter
Stark, Richard J.
Synofzik, Matthis
Taba, Pille
Tagliavini, Fabrizio
Thakur, Kiran T.
Umapathi, Thirugnanam
Vijayabala, Jeevagan
Weissenborn, Karin
Wijeratne, Tissa
Wood MRes, Greta K
Carroll, William M.
Oreja‐Guevara, Celia
Leonardi, Matilde
Schmutzhard, Erich
29 Mar 2021
A Haemagglutination test for rapid detection of antibodies to SARS-CoV-2
Townsend, Alain
Rijal, Pramila
Xiao, Julie
Tan, Tiong Kit
Huang, Kuan-ying A
Schimanski, Lisa
Huo, Jiandong
Gupta, Nimesh
Rahikainen, Rolle
Matthews, Philippa C
Crook, Derrick
Hoosdally, Sarah
Dunachie, Susanna
Barnes, Eleanor
Street, Teresa
Semple, Malcolm G
Turtle, Lance C W
Ainsworth, Mark
Allcock, Alice
Beer, Sally
26 Mar 2021
Assessing the suitability for Aedes albopictus and dengue transmission risk in China with a delay differential equation model
Metelmann, Soeren
Liu, Xiaobo
Lu, Liang
Caminade, Cyril
Liu, Keke
Cao, Lina
Medlock, Jolyon M.
Baylis, Matthew
Morse, Andrew P.
Liu, Qiyong
26 Mar 2021
Assessing the suitability for Aedes albopictus and dengue transmission risk in China with a delay differential equation model
HPRU-EZI Authors -
Medlock, Jolyon M.
Baylis, Matthew
21 Mar 2021
SARS-CoV-2 Infections in Animals: Reservoirs for Reverse Zoonosis and Models for Study
Prince, Tessa
Smith, Shirley L
Radford, Alan D
Solomon, Tom
Hughes, Grant L
Patterson, Edward I
21 Mar 2021
Long-term neurodevelopment outcomes of hand, foot and mouth disease inpatients infected with EV-A71 or CV-A16, a retrospective cohort study
HPRU-EZI Authors-
Lance Turtle
21 Mar 2021
Systematic review of pooling sputum as an efficient method for xpert MTB/RIF tuberculosis testing during COVID-19 pandemic. Emerg Infect Dis. 2021;27(3):719–27
HPRU-EZI Authors -
Cuevas, Luis E.,
Adams, Emily
17 Mar 2021
Prospective observational study of SARS-CoV-2 infection, transmission and immunity in a cohort of households in Liverpool City Region, UK (COVID-LIV): a study protocol
Setiabudi, Wega
Hungerford, Daniel
Subramaniam, Krishanthi
Vaselli, Natasha Marcella
Shaw, Victoria E
Wilton, Moon
Vivancos, Roberto
Aston, Stephen
Platt, Gareth
Moitt, Tracy
Jones, Ashley P
Gabbay, Mark
Buchan, Iain
Carrol, Enitan D
Iturriza-Gomara, Miren
Solomon, Tom
Greenhalf, William
Naisbitt, Dean J
Adams, Emily R
Cunliffe, Nigel A
Turtle, Lance
French, Neil
17 Mar 2021
Obesity, Ethnicity, and Risk of Critical Care, Mechanical Ventilation, and Mortality in Patients Admitted to Hospital with COVID‐19: Analysis of the ISARIC CCP‐UK Study. J. Obesity
HPRU-EZI Authors
Semple, Malcolm G.
10 Mar 2021
Inflammatory profiles across the spectrum of disease reveal a distinct role for GM-CSF in severe COVID-19
Thwaites, Ryan S
Sanchez Sevilla Uruchurtu, Ashley
Siggins, Matthew K
Liew, Felicity
Russell, Clark D
Moore, Shona C
Fairfield, Cameron
Carter, Edwin
Abrams, Simon
Short, Charlotte-Eve
Thaventhiran, Thilipan
Bergstrom, Emma
Gardener, Zoe
Ascough, Stephanie
Chiu, Christopher
Docherty, Annemarie B
Hunt, David
Crow, Yanick J
Solomon, Tom
Taylor, Graham P
Turtle, Lance
Harrison, Ewen M
Dunning, Jake
Semple, Malcolm G
Baillie, J Kenneth
Openshaw, Peter JM
10 Mar 2021
Inflammatory profiles across the spectrum of disease reveal a distinct role for GM-CSF in severe COVID-19
HPRU-EZI Authors:
Tom Solomon,
Lance Turtle,
Calum Semple,
Jake Dunning
05 Mar 2021
Torix Rickettsia are widespread in arthropods and reflect a neglected symbiosis
Pilgrim, Jack
Thongprem, Panupong
Davison, Helen
Siozios, Stefanos
Baylis, Matthew
Zakharov, Evgeny V.
Ratnasingham, Sujeevan
DeWaard, Jeremy R.
Smith, M. Alex
Hurst, Gregory D. D.
04 Mar 2021
Circulating SARS-CoV-2 spike N439K variants maintain fitness while evading antibody-mediated immunity
HPRU-EZI Author -
Calum Semple
04 Mar 2021
Risk of adverse outcomes in patients with underlying respiratory conditions admitted to hospital with COVID-19: a national, multicentre prospective cohort study using the ISARIC WHO Clinical Characterisation Protocol UK
HPRU-EZI Authors:
Calum Semple,
Jake Dunning
25 Feb 2021
Long Covid in adults discharged from UK hospitals after Covid-19 : A prospective , multicentre cohort study using the ISARIC WHO Clinical Characterisation Protocol Author Affiliations :
HPRU-EZI Authors -
Sigfrid, Louise
Goodwin, Lynsey
Turtle, Lance
Semple, Malcom G
21 Feb 2021
Modelling intensive care unit capacity under different epidemiological scenarios of the COVID-19 pandemic in three Western European countries
McCabe R, Kont MD, Schmit N, Whittaker C, Løchen A, Baguelin M,
16 Feb 2021
Predicting mammalian hosts in which novel coronaviruses can be generated
Maya Wardeh Matthew Baylis, Marcus S. C. Blagrove
15 Feb 2021
Sequential infection with influenza A virus followed by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) leads to more severe disease and encephalitis in a mouse model of COVID-19.
Jordan J. Clark , Rebekah Penrice-Randal , Parul Sharma , Anja Kipar , Xiaofeng Dong , Shaun H. Pennington ,
Amy E. Marriott , Stefano Colombo , Andrew Davidson , Maia Kavanagh Williamson , David A. Matthews ,
Lance Turtle , Tessa Prince , Grant L. Hughes , Edward I. Patterson , Ghada Shawli ,
Krishanthi Subramaniam , Jo Sharp , Lynn McLaughlin , En-Min Zhou , Joseph D. Turner ,
Giancarlo Biagini , Andrew Owen , Julian A. Hiscox, James P. Stewart
08 Feb 2021
Cardinium symbiosis as a potential confounder of mtDNA based phylogeographic inference in Culicoides imicola (Diptera: Ceratopogonidae), a vector of veterinary viruses. Parasit Vectors [Internet]. 2021;14(1):1–5
HPRU-EZI Authors -
Matthew Baylis
03 Feb 2021
Impact of climatic, demographic and disease control factors on the transmission dynamics of COVID-19 in large cities worldwide
Metelmann, Soeren
Pattni, Karan
Brierley, Liam
Cavalerie, Lisa
Caminade, Cyril
Blagrove, Marcus S.C.
Turner, Joanne
Sharkey, Kieran J.
Baylis, Matthew
27 Jan 2021
Ebola virus antibody decay – stimulation in a high proportion of survivors
Adaken, Charlene
Scott, Janet T
Sharma, Raman
Gopal, Robin
Dicks, Steven
Niazi, Saidia
Ijaz, Samreen
Edwards, Tansy
Smith, Catherine C
Cole, Christine P
21 Jan 2021
Mayaro Virus Infection Elicits an Innate Immune Response and Represses Autophagy in Anopheles stephensi
Cory Henderson, Marco Brustolin, Shivanand Hegde, Grant L. Hughes, Christina Bergey, Jason L. Rasgon
19 Jan 2021
English hospital episode data analysis (1998–2018) reveal that the rise in dog bite hospital admissions is driven by adult cases
John S. P. Tulloch 1,2,3*, Sara C. Owczarczak‐Garstecka 3,4,5, Kate M. Fleming 6, Roberto Vivancos 2,7 & Carri Westgarth 3
13 Jan 2021
COVID-19 testing in outbreak free care homes: What are the public health benefits?
Green, R.
Tulloch, J.S.P.
Tunnah, C.
Coffey, E.
Lawrenson, K.
Fox, A.
Mason, J.
Barnett, R.
Constantine, A.
Shepherd, W.
Ashton, M.
Beadsworth, M.B.J.
Vivancos, R.
Hall, I.
Walker, N.
Ghebrehewet, S.
11 Jan 2021
Analysis of an Ebola virus disease survivor whose host and viral markers were predictive of death indicates the effectiveness of medical countermeasures and supportive care
Bosworth, Andrew
Rickett, Natasha Y.
Dong, Xiaofeng
Ng, Lisa F.P.
García-Dorival, Isabel
Matthews, David A.
Fletcher, Tom
Jacobs, Michael
Thomson, Emma C.
Carroll, Miles W.
Hiscox, Julian A.
11 Jan 2021
Development and validation of the ISARIC 4C Deterioration model for adults hospitalised with COVID-19: a prospective cohort study
HPRU-EZI Authors:
Tom Solomon,
Lance Turtle,
Calum Semple,
Jake Dunning
07 Jan 2021
Neurological infection with SARS-CoV-2 — the story so far
Solomon, Tom