The overarching aim of the HPRU is to support and strengthen PHE in its role of protecting England from emerging and zoonotic infections. By bringing together internationally leading researchers at the University of Liverpool (UoL), University of Oxford, Liverpool School of Tropical Medicine (LSTM) and PHE, we exploit the synergy, world-class facilities, and breadth and depth in relevant research between these institutions.


Latest News


Major UK Study of Cancer and COVID-19 Launched
A new UK study has been launched to assess the impact of COVID-19 on people with cancer.

Posted on: 08/09/2020

Coronavirus: 'Reassuring' study of children's 'tiny' risk
Professor Calum Semple speaks to BBC Northwest Tonight about Covid-19 in children.

Posted on: 03/09/2020

Liverpool Responds: UK immunologists join forces to search for answers on COVID-19
Today sees the launch of the new UK Coronavirus Immunology Consortium (UK-CIC), which aims to address key unanswered questions about immunity and COVID-19 to help develop better diagnostics, treatments and vaccines. The Liverpool Outbreak Laboratories will support this major collaboration of 17 UK institutions, who are combining their research expertise to fight the coronavirus pandemic. The consortium has received £6.5million of funding over 12 months from UK Research and Innovation (UKRI) and the National Institute for Health Research (NIHR), the largest immunology grant awarded to tackle the COVID-19 pandemic.

Posted on: 28/08/2020

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BMJ Best Practice Coronavirus Disease (COVID-19)
Nicholas J Beeching, Tom E Fletcher, Robert Fowler
BMJ Best Practice, 

Characterisation of the transcriptome and proteome of SARS-CoV-2 using direct RNA sequencing and tandem mass spectrometry reveals evidence for a cell passage induced in-frame deletion in the spike glycoprotein that removes the furin-like cleavage site
Andrew D. Davidson, Maia Kavanagh Williamson, Sebastian Lewis, Deborah Shoemark, Miles W. Carroll, Kate Heesom, Maria Zambon, Joanna Ellis, Phillip A. Lewis, Julian A. Hiscox,  View ORCID ProfileDavid A. Matthews

Amplicon based MinION sequencing of SARS-CoV-2 and metagenomic characterisation of nasopharyngeal swabs from patients with COVID-19
Shona C Moore, Rebekah Penrice-Randal, Muhannad Alruwaili, Xiaofeng Dong, Steven T Pullan, Daniel Carter, Kevin Bewley, Qin Zhao, Yani Sun, Catherine Hartley, En-min Zhou, Tom Solomon, Michael B. J. Beadsworth, James Cruise, Debby Bogaert, Derrick W T Crook, View ORCID ProfileDavid A Matthews, Andrew D. Davidson, Zana Mahmood, Waleed Aljabr, Julian Druce, Richard T Vipond, Lisa Ng, Laurent Renia, Peter Openshaw, View ORCID ProfileJ Kenneth Baillie, Miles W Carroll, Calum Semple, Lance Turtle, Julian Alexander Hiscox

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