Ebola virus disease

Authors:

Beeching NJ, Fenech M, Houlihan CF

Abstract:

The bottom line

  • Ebola virus disease is a severe, often fatal, zoonotic infection caused by a virus of the Filoviridae family (genus Ebolavirus)

  • Human to human transmission occurs through contact with body fluids from infected patients. The incubation period after infection is 1-21 days and patients are not considered infectious until they develop symptoms

  • Initial stages of infection are non-specific, which makes the differential diagnosis broad. A history of exposure and clinical suspicion of infection should prompt isolation

  • Management is currently focused on supportive care and infection control. Healthcare workers should familiarise themselves with local guidance

  • Case fatality rates range from 30% to 90%

  • Because of the high likelihood of infected people travelling, all countries should have tested and practised protocols ready for screening and managing patients

Journal:

BMJ

Year:

2014

PMID:

25497512

Hyperlink:

http://bmj.com/cgi/content/full/bmj.g7348

Research Themes:

Clinical Surveillance